Our projects in immunotherapy gene transfer highlights our experience
in cell & gene therapy. These are the major ones:
Immunotherapy
Treatment of viral infections using donor-derived cells; viral-specific T cells were generated – using cells of the donor who initially donated HSCT for the bone marrow transplant – to protect or treat infections of Adv, CMV, EBV, and BKV. clinicaltrials.gov identifier NCT02048332
Treatment of viral infection using 3rd Party cells; viral-specific T cells were generated using cells of unrelated donor (3rd party) to protect or treat infections of Adv, CMV, EBV, and BKV. clinicaltrials.gov identifier NCT02532452
Gene Transfer
Treatment of Sickle cell disease; CD34+ patient’ cells transduced with the gamma-globin lentiviral vector then infused back in patient for the correction of sickle cell disease. clinicaltrials.gov identifier NCT02186418
Treatment of Multiple Myeloma; generating autologous Chimeric antigen receptor (CAR) T cells for the treatment of relapse/refractory (R/R) multiple myeloma. clinicaltrials.gov identifier NCT03090659