{"id":458,"date":"2024-08-28T21:21:20","date_gmt":"2024-08-28T21:21:20","guid":{"rendered":"http:\/\/b6d.c53.mytemp.website\/home\/uncategorized\/built-in-quality-the-what-and-how\/"},"modified":"2024-09-01T17:24:37","modified_gmt":"2024-09-01T17:24:37","slug":"built-in-quality-the-what-and-how","status":"publish","type":"post","link":"https:\/\/potentcells.com\/home\/uncategorized\/built-in-quality-the-what-and-how\/","title":{"rendered":"Built-in Quality, the what and how"},"content":{"rendered":"
2021-12-28T05:00:00.000Z<\/p>\n

I have previously mentioned the built-in quality in multiple posts, and I thought, maybe I should dedicate a post to discuss it a little further. I apologize in advance to our quality folks for maybe not using their terminology, I want to explain the built-in quality in simpler terms.<\/p>\n

Built-in Quality Defined<\/strong><\/p>\n

You hear the term built-in a lot in electronics world, but in laboratory world! In electronics, built-in indicate that certain feature(s) are included as integral part of your gadget, like built-in speaker or camera. Built-in quality means that the \u201cquality\u201d feature is an integral part of your process; sounds exciting, right?<\/p>\n

Built-In Quality, How To?\u00a0<\/strong><\/p>\n

Building quality in your process is composed of two phases:<\/p>\n

Phase I<\/strong>. Identify the quality points in the relevant steps of your process; these are the points that if not controlled could negatively impact the rest of the process. Identifying these points requires a knowledge \/ experience of the process. Let me list few examples:<\/p>\n

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  1. From the 100+ products your laboratory had processed, you know that a final concentration of 10%-15% of anticoagulant in your starting product is the suite point that prevents clotting without negatively impacting the cells viability, i.e., when controlled, you get to work with a product of high quality.<\/li>\n
  2. The literature supports your experience that turning the \u201cBreak\u201d off during product centrifugation results in a quality separation; clearly defined layers.<\/li>\n
  3. In programming the magnetic activated cell sorter (MACS) you found that having a second technologist to verify the programming process eliminates the programming-related errors and results in a quality selection with no deviations.<\/li>\n<\/ol>\n

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    Phase II<\/strong>. Implementing the quality points in your process. This phase requires that you:<\/p>\n

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